https://tedebc.ufma.br/jspui/handle/tede/1282 2026-06-10T06:29:53Z https://tedebc.ufma.br/jspui/handle/tede/7039 Título: AVALIAÇÃO IN VITRO DA ATIVIDADE ANTIFÚNGICA DE EXTRATOS VEGETAIS SOBRE CANDIDA SPP. Autor: NUNES, Marjorie Adriane da Costa Primeiro orientador: PEREIRA , Antônio Luiz Amaral Abstract: Candida yeasts are often associated with normal oral mucosa. However, in specific situations, such as immunological, chemical and mechanical changes, can trigger infections called candidiasis. When associated with the use of prostheses, candidiasis is called denture stomatitis. Candida biofilm is considered the main etiological factor in denture stomatitis basis of the prosthesis and its removal is necessary by the use of chemical cleaners associated or not to antifungal agents. Given this, the objective of this study was to evaluate the antifungal potential of plant extracts on Candida spp. and on biofilm formed in acrylic resin specimens. We conducted laboratory study, in vitro, by analyzing the performance of plant extracts (Passiflora edulis leaves and Psidium guajava L., peel Schinus terebinthifolius Raddi, mesocarp Orbignya phalerata Mart. And leaves and bark of Anacardium occidentale L. ) at a concentration of 100mg / ml of standard strains C. albicans (ATCC90028) and C. glabrata (ATCC2001). The antimicrobial activity was evaluated by the agar diffusion method, determination of minimum inhibitory concentration (MIC) by microdilution broth method, followed by the subcultures in agar to determine the concentration Fungicide Min. The positive controls were 0.12% chlorhexidine gluconate and fluconazole 128 mg / mL. It was also evaluated the effect of Psidium guajava extract of C. albicans biofilm (ATCC90028) formed on acrylic resin specimens. The specimens were submitted to the treatments: herbal extract of Psidium guajava in the concentration of 300mg / ml (15 min); Sodium hypochlorite (NaOCl) 0.5% (10 min) as positive control and negative control as distilled and deionized water (15 min). The number of viable Candida cells was expressed as colony forming units (CFU) / mm2. The Psidium guajava L. extract presented halos of inhibition of 17.08 mm for C. albicans and C. glabrata to 20.41 mm. The other extracts did not form inhibition zones for the tested strains. The MIC and MFC of Psidium guajava extract for C. albicans was 15mg / ml and 30mg / ml respectively and C. glabrata 3.75mg / ml and 15mg / ml. With respect to the effect of the extract on the biofilm, it was observed a significant reduction in CFUs acrylic resin specimens when compared to the negative control group. It was concluded in this study that the extract of Psidium guajava leaves showed antifungal activity against strains of C. albicans and C. glabrata and that it significantly reduced the biofilm formed on the acrylic resin specimens. Instituição: Universidade Federal do Maranhão Tipo do documento: Dissertação 2015-05-28T00:00:00Z https://tedebc.ufma.br/jspui/handle/tede/7012 Título: Tendências de gastos com cuidados odontológicos por provedores e serviços de saúde, e Quintis do índice sociodemográfico em 195 países, de 2000 a 2017 Autor: CAMPOS, Handreza Régia Santos Siqueira Primeiro orientador: HUGO, Fernando Neves Abstract: The number of people affected by oral diseases in the world is approximately 3.5 billion. In this scenario, dental care spending is uneven across countries. Health expenditure analyses have been conducted to understand the current global health financing situation and to assist in health planning. The objective of this study is to describe trends in dental care spending, by health providers and services, and by Socio-Demographic Index quintiles in 195 countries, between 2000 and 2017. Health account data were extracted from 195 countries and expenditures categorized according to the System of Health Accounts. Missing or non-existent data were estimated using a Bayesian multivariate model to construct complete time series. Spending trends were measured using generalized linear regression and the Prais-Winsten method. The results showed that per capita expenditure and total expenditure, in millions of dollars, on dental care by total and outpatient/clinical service providers revealed a clear gradient, with values increasing with greater socioeconomic development. In 2017, countries in high quintile had per capita expenditure 278 and 93 times higher than countries in the low and lower-middle quintile, respectively. Dental expenditure represented a small share in relation to total health expenditure, regardless of the level of development of the countries (in 2017, low quintile – 2,55% and high – 4,66%). In the trend analysis, all quintiles showed an increase in per capita expenditure and total dental expenditure, in relation to total dental providers and outpatient/clinical care. It was concluded that there were large inequalities in the distribution by levels of economic development in dental care spending. To date, this work is the most comprehensive proposal for analyzing trends in dental care expenditure. The findings of this study can help managers identify the prioritization that has been given to public oral health policies, also considering the context of the Universal Health Coverage Agenda, the Global Oral Health Strategy and the Sustainable Development Goals. Instituição: Universidade Federal do Maranhão Tipo do documento: Dissertação 2024-10-14T00:00:00Z https://tedebc.ufma.br/jspui/handle/tede/6995 Título: Potencial terapêutico do polissacarídeo da goma do cajueiro e sua associação com fluoreto na mitigação da erosão dentinária exposta a um modelo in vitro de refluxo gastroesofágico: análise mecânica, morfológica e colagenolítica Autor: MENDES, Thaysa Fernandes Pinto Primeiro orientador: FIRROZMAND, Leily Macedo Abstract: Aguardando envio Instituição: Universidade Federal do Maranhão Tipo do documento: Tese 2026-03-02T00:00:00Z https://tedebc.ufma.br/jspui/handle/tede/6992 Título: TENDÊNCIA TEMPORAL DA CÁRIE NA PRIMEIRA INFÂNCIA E DOENÇAS NÃO-TRANSMISSÍVEIS: GLOBAL BURDEN OF DISEASE STUDY 2021 Autor: COSTA, Cayara Mattos Primeiro orientador: RIBEIRO, Cecilia Claudia Costa Abstract: This work addresses early childhood caries, specifying the temporal trend and aspects such as asthma and obesity, which are intervening factors. Instituição: Universidade Federal do Maranhão Tipo do documento: Tese; Trabalho sob sigilo.Motivo do sigilo: O artigo 1 foi publicado em revista que não permite a divulgação.Prazo previsto para disponibilização total: Não há. 2026-03-27T00:00:00Z